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Lung Cancer

  • REZILIENT3: randomized phase III study of first-line zipalertinib plus chemotherapy in patients with EGFR exon 20 insertion-mutated NSCLC

    Heymach JV, Yu HA, Besse B, et al. Future Oncol. 2025;21(5):549–556

  • Zipalertinib in Patients With EGFR Exon 20 Insertion-Positive NSCLC Previously Treated With Platinum-Based Chemotherapy With or Without Amivantamab

    Piotrowska Z, Passaro A, Nguyen D, et al. J Clin Oncol. 2025;43(21):2387–2397

  • Safety, Tolerability, and Antitumor Activity of Zipalertinib Among Patients With Non-Small-Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 20 Insertions

    Piotrowska Z, Tan DSW, Smit EF, et al. J Clin Oncol. 2023;41(26):4218–4225

  • TAS6417/CLN-081 Is a Pan-Mutation-Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations

    Udagawa H, Hasako S, Ohashi A, et al. Mol Cancer Res. 2019;17(11):2233–2243

  • TAS6417, A Novel EGFR Inhibitor Targeting Exon 20 Insertion Mutations

    Hasako S, Terasaka M, Abe N, et al. Mol Cancer Ther. 2018;17(8):1648–1658